Oh YES it can
2012 Ford Flex
Crutchfield Customer Review (What's this?)
Ford had nothing for me related to getting a GPS built in. Scosche did! This kit sets the unit to a lower position, but it works!
Pros: I'm done with the wires hanging everywhere for a portable GPS. It fits like a glove.
Cons: You do have to transfer some of the switches. The lower ones are moved up to the upper area. Takes a little bit of time, but not a difficult procedure.